Cell Theory

Cell Theory:

In 1839, Schleiden and Schwann collaboratively introduced the “Cell Theory,” asserting that all living organisms consist of cells, which serve as the fundamental structural and functional units for all organisms.

Development of Cell Theory:

Studying the sequential development of cell theory provides insight into the functioning of scientific methodology. This process involves distinct stages: 1. Observation, 2. Hypothesis, 3. Formulation of theory, and 4. Modification of theory if necessary. The initial observations crucial to cell theory were conducted by Schleiden (1804 – 1881), a German botanist. Through an extensive examination of various plants, he discovered that all of them were comprised of cells. By 1838, he had deduced that cells represent the fundamental structural units of all plant tissues.

Another key contributor, Schwann, a German zoologist, extended this understanding through his examination of various animal types. He observed that animal cells lacked a cell wall and were enveloped by a membrane. Schwann asserted that, aside from the cell wall, animal cells and plant cells shared fundamental similarities. Both contained a nucleus surrounded by a clear substance. He defined the cell as a structure encapsulating a nucleus within a membrane. Schwann proposed a hypothesis that posited the bodies of animals and plants as being composed of cells and their respective products.

Schleiden and Schwann collaborated to deliberate on Schwann’s hypothesis, ultimately giving rise to the formulation of cell theory. The key tenets of this theory encompass the following principles:

  1. All living organisms consist of diminutive units known as cells, representing the smallest entities considered alive.
  2. Each cell comprises a protoplasm containing a nucleus and is encased by a plasma membrane, sometimes accompanied by a cell wall.
  3. Cells, irrespective of their origin, share fundamental similarities in both structure and metabolic functions.
  4. The overall function of an organism arises from the collective activities and interactions of its individual constituent cells.

Exception to cell Theory:

Viruses present a perplexing challenge for biologists, deviating from the established cell theory as they lack protoplasm—the essential component of cells. Bacteria and cyanobacteria, such as Blue-Green algae, exhibit an absence of a well-organized nucleus. Some protozoans are classified as acellular. In certain fungi, like Rhizopus, the coenocytic hyphae display an undivided mass of protoplasm with scattered nuclei. Notably, both Red Blood Corpuscles (RBC) and mature sieve tubes exist without nuclei. Moreover, cells in close proximity can undergo varied physiological states, such as growth, secretion, division, or death, challenging the traditional understanding of uniform cellular behavior. These revelations have prompted modifications to the cell theory, leading to an elevated status known as the cell principle or cell doctrine for the adapted form of this foundational concept.

Cell Principle or Cell Doctrine:

The fundamental tenets of the cell doctrine include:

  1. Every living organism is composed of cells.
  2. Pre-existing cells give rise to new cells.
  3. The cell serves as the fundamental structural and functional unit in all living organisms.
  4. Within a cell, hereditary information is contained and passed on during cell division.
  5. Cells exhibit a fundamental similarity in both chemical composition and metabolic activities.
  6. DNA governs the structure and function of the cell.
  7. In certain instances, non-living cells such as tracheids and vessels in plants or keratinized cells in animals can persist and maintain functionality even after death.

Cell Types:

Prokaryotes- Prokaryotes are typically compact cells enclosed by a plasma membrane, featuring distinct cell walls of varying compositions depending on the species. Lacking a nucleus and membrane-bound organelles, prokaryotes harbor circular or linear DNA within their protoplasm, housing both the chromosomal region and the cytoplasm. The prokaryotic domain comprises two classifications: archaea and bacteria.

Eukaryotes- In contrast, eukaryotic cells boast a nucleus, organelles, and a surrounding plasma membrane. The evolution of eukaryotic cells led to the development of specialized organelles, each with a specific function. Notable examples include the endoplasmic reticulum, responsible for sorting and bundling proteins; mitochondria, which generate energy; and chloroplasts, exclusive to plants, producing food through the utilization of sunlight and carbon dioxide.


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